الصفحة الرئيسية>>Signaling Pathways>> Antibody-drug Conjugate/ADC Related>> ADC Linker>>m-PEG6-CH2CH2CHO

m-PEG6-CH2CH2CHO

رقم الكتالوجGC65828

إن m-PEG6-CH2CH2CHO عبارة عن رابط ADC غير قابل للكسر يُستخدم في تخليق اتحادات الأجسام المضادة والأدوية (ADCs). m-PEG6-CH2CH2CHO هو أيضًا رابط PROTAC قائم على PEG ويمكن استخدامه في تركيب PROTACs.

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m-PEG6-CH2CH2CHO التركيب الكيميائي

Cas No.: 1058691-77-2

الحجم السعر المخزون الكميّة
100mg
194٫40
متوفر
250mg
372٫60
متوفر

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مراجعات العميل

بناء على آراء العملاء.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

m-PEG6-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-CH2CH2CHO is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

مراجعات

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