m-PEG6-CH2CH2CHO |
Catalog No.GC65828 |
m-PEG6-CH2CH2CHO는 항체-약물 접합체(ADC)의 합성에 사용되는 절단 불가능한 ADC 링커입니다. 821d96072c2d58d8970e76f526b0f6b8m-PEG6-CH2CH2CHO는 또한 PROTAC 합성에 사용될 수 있는 PEG 기반 PROTAC 링커입니다.821d96072c2d58d8970e76f526b0f6b8
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Cas No.: 1058691-77-2
Sample solution is provided at 25 µL, 10mM.
m-PEG6-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-CH2CH2CHO is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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