MLK-IN-1 |
رقم الكتالوجGC64634 |
MLK-IN-1 هو مثبط قوي ، مخترق للدماغ ومثبط محدد من نسب كيناز 3 (MLK-3) ، مركب 68 ، مستخلص من براءة الاختراع US20140256733A1
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Cas No.: 1627729-62-7
Sample solution is provided at 25 µL, 10mM.
MLK-IN-1 is a potent, brain penetrant and specific mixed lineage kinase 3 (MLK-3) inhibitor, compound 68, extracted from patent US20140256733A1[1].
MLK-IN-1 (100 nM; pre-treatment 20 mins HIV-1 Tat) promotes continued axonogenesis in the presence of Tat-activated microglia and protects against effects of HIV-Tat in vitro[1].
[1]. Val S. Goodfellow,et al.Mixed lineage kinase inhibitors and method of treatments. Patent US20140256733A1.
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