Monactin |
| رقم الكتالوجGC40613 |
Monactin هو مضاد حيوي mactrotetralide وحامل شون غير انتقائي للكاتيونات أحادية التكافؤ ، بما في ذلك البوتاسيوم والصوديوم والليثيوم
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 7182-54-9
Sample solution is provided at 25 µL, 10mM.
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Monactin is a mactrotetralide antibiotic originally isolated from Streptomyces and a non-selective ionophore for monovalent cations, including potassium, sodium, and lithium. It has low antimicrobial activity but is more active than its homolog nonactin . Monactin induces swelling of rat liver mitochondria in medium containing either potassium or sodium, stimulates respiration, and uncouples oxidative phosphorylation. It also inhibits Wnt signaling via inhibition of TCF-β-catenin transcriptional activity.
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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