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Monactin

カタログ番号GC40613

モナクチンはマクロテトラリド系抗生物質であり、カリウム、ナトリウム、リチウムなどの一価陽イオンに対する非選択的イオノフォアです。

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Monactin 化学構造

Cas No.: 7182-54-9

サイズ 価格 在庫数 個数
1mg
$361.00
在庫あり
5mg
$1,350.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Monactin is a mactrotetralide antibiotic originally isolated from Streptomyces and a non-selective ionophore for monovalent cations, including potassium, sodium, and lithium. It has low antimicrobial activity but is more active than its homolog nonactin . Monactin induces swelling of rat liver mitochondria in medium containing either potassium or sodium, stimulates respiration, and uncouples oxidative phosphorylation. It also inhibits Wnt signaling via inhibition of TCF-β-catenin transcriptional activity.

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Average Rating: 5 ★★★★★ (Based on Reviews and 38 reference(s) in Google Scholar.)

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