MRS 1754 |
| رقم الكتالوجGC13807 |
MRS 1754 عبارة عن مركب إشعاعي مضاد انتقائي لمستقبلات الأدينوزين A2B مع تقارب منخفض جدًا لمستقبلات A1 و A3 لكل من البشر والجرذان
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Cas No.: 264622-58-4
Sample solution is provided at 25 µL, 10mM.
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MRS 1754 is a selective antagonist radioligand for A2B adenosine receptor with very low affinity for A1 and A3 receptors of both humans and rats[1].
The most potent displacer of [3H]MRS 1754 binding is MRS 1754. The Ki value for displacement of [3H]MRS 1754 binding to human A2B receptors expressed in HEK-293 cell membranes is 1.45±0.21 nM[1].
References:
[1]. Ji X, et al. [3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors. Biochem Pharmacol. 2001 Mar 15;61(6):657-63.
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