الصفحة الرئيسية>>Signaling Pathways>> PROTAC>>NH2-PEG2-CH2-Boc

NH2-PEG2-CH2-Boc

رقم الكتالوجGC61417

NH2-PEG2-CH2-Boc عبارة عن رابط PROTAC قائم على PEG يمكن استخدامه في تركيب PROTACs

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NH2-PEG2-CH2-Boc التركيب الكيميائي

Cas No.: 1948273-09-3

الحجم السعر المخزون الكميّة
100 mg
221٫00
متوفر
250 mg
410٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com

مراجعات العميل

بناء على آراء العملاء.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

NH2-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

مراجعات

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