NLS (PKKKRKV) (hydrochloride) |
| رقم الكتالوجGC61806 |
هيدروكلوريد NLS (PKKKRKV) هو إشارة توطين نووي (NLS) مشتقة من مستضد الورم الكبير 40 لفيروس القردة (مستضد SV40 كبير T)يمكن أن يعمل NLS (PKKKRKV) كطريقة لتعزيز الدخول النووي في مجال أبحاث نقل الجينات
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Sample solution is provided at 25 µL, 10mM.
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NLS (PKKKRKV) hydrochloride is a nuclear localization signal (NLS) derived from the simian virus 40 large tumor antigen (SV40 large T antigen). NLS (PKKKRKV) can function as a method to enhance nuclear entry in the field of gene transfer research[1][2].
[1]. Zanta MA, et al. Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc Natl Acad Sci U S A. 1999 Jan 5;96(1):91-6. [2]. Cao S, et al. Enhanced effect of nuclear localization signal peptide during ultrasound-targeted microbubble destruction-mediated gene transfection. Mol Med Rep. 2017 Jul;16(1):565-572.
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