NLS (PKKKRKV) (hydrochloride) |
| カタログ番号GC61806 |
NLS (PKKKRKV) 塩酸塩は、サルウイルス 40 ラージ腫瘍抗原 (SV40 ラージ T 抗原) に由来する核局在化シグナル (NLS) です。 NLS (PKKKRKV) は、遺伝子導入研究の分野で核侵入を促進する方法として機能します。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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NLS (PKKKRKV) hydrochloride is a nuclear localization signal (NLS) derived from the simian virus 40 large tumor antigen (SV40 large T antigen). NLS (PKKKRKV) can function as a method to enhance nuclear entry in the field of gene transfer research[1][2].
[1]. Zanta MA, et al. Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc Natl Acad Sci U S A. 1999 Jan 5;96(1):91-6. [2]. Cao S, et al. Enhanced effect of nuclear localization signal peptide during ultrasound-targeted microbubble destruction-mediated gene transfection. Mol Med Rep. 2017 Jul;16(1):565-572.
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