Peramivir Trihydrate |
| رقم الكتالوجGC13110 |
بيراميفير ثلاثي هيدرات (RWJ-270201 ثلاثي هيدرات ؛ BCX-1812 ثلاثي هيدرات) هو مثبط قوي للغاية ، انتقائي ونشط فمويًا لفيروس الأنفلونزا (NA) ، مع قيم IC50 تتراوح من 0.9 إلى 4.3 نانومتر لتسعة أنواع فرعية من NA
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1041434-82-5
Sample solution is provided at 25 µL, 10mM.
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Peramivir trihydrate (RWJ-270201 trihydrate;BCX-1812 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes[1][2].
References:
[1]. Babu YS, et al. BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design. J Med Chem. 2000 Sep 21;43(19):3482-6.
[2]. Young D, et al. RWJ-270201 (BCX-1812): a novel neuraminidase inhibitor for influenza. Philos Trans R Soc Lond B Biol Sci. 2001 Dec 29;356(1416):1905-13.
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