PFM 01 |
| رقم الكتالوجGC50388 |
PFM 01 ، مشتق ميرين N-alkylated ، هو مثبط نوكلياز MRE11. يمكن أن ينظم PFM 01 إصلاح الكسر المزدوج (DSBR) عن طريق الالتحام غير المتماثل (NHEJ) مقابل إعادة التركيب المتماثل (HR).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1558598-41-6
Sample solution is provided at 25 µL, 10mM.
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MRE11 endonuclease inhibitor. Prevents double-stranded break (DSB) resection. Enhances non-homologous end-joining (NHEJ) and reduces homologous recombination.
Shibata et al (2014) DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities. Mol.Cell 53 7 PMID:24316220
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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