Pinosylvin (Synonyms: trans-3,5-Dihydroxystilbene) |
| رقم الكتالوجGC40861 |
Pinosylvin هو توكسين stilbenoid سام قبل العدوى معزول من خشب القلب من Pinus spp ، وله أنشطة مضادة للبكتيريا
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Cas No.: 22139-77-1
Sample solution is provided at 25 µL, 10mM.
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Pinosylvin is a stilbene originally isolated from pine heartwood that has diverse biological activities. It activates sirtuin 1 (SIRT1) and induces glucose uptake in isolated rat L6 skeletal muscle myotubes. Pinosylvin reduces radial growth in a panel of 28 plant pathogenic fungi when used at a concentration of 100 μg/ml. It reduces expression of matrix metalloproteinase-2 (MMP-2), MMP-9, and membrane type 1-MMP in and inhibits migration of HT-1080 cells. Pinosylvin (10 mg/kg, i.p.) reduces the number of tumor nodules and lung tumor weight in a CT26 mouse xenograft model of metastatic colon cancer. It decreases hind paw volume and myeloperoxidase (MPO) activity in a rat model of adjuvant-induced arthritis. Pinosylvin also exhibits plant antifeedant activity against L. americanus (snowshoe hares).
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