Podophyllotoxone |
رقم الكتالوجGC64705 |
يتم عزل بودوفيلوتوكسون من جذور عسر الهضم وله أنشطة مضادة للسرطان. بودوفيلوتوكسون قادر على تثبيط بلمرة التوبولين
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Cas No.: 477-49-6
Sample solution is provided at 25 µL, 10mM.
Podophyllotoxone is isolated from the roots of Dysosma versipellis and has anti-cancer activities.Podophyllotoxone is able to inhibit the tubulin polymerization[1].
Podophyllotoxone inhibits human prostate cancer cells PC3 and DU145 growth with IC50 values of 14.7 and 20.6 µM[1].
[1]. Juan Li , et al. Absolute Configuration of Podophyllotoxone and Its Inhibitory Activity Against Human Prostate Cancer Cells. Chin J Nat Med. 2015 Jan;13(1):59-64.
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