الصفحة الرئيسية>>Signaling Pathways>> Apoptosis>> KEAP1-Nrf2>>RA 839

RA 839

رقم الكتالوجGC50242

منشط Nrf2؛ يثبط تفاعل Nrf2 / Keap1

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RA 839 التركيب الكيميائي

Cas No.: 1832713-02-6

الحجم السعر المخزون الكميّة
10 mg
265٫00
متوفر
50 mg
756٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com

مراجعات العميل

بناء على آراء العملاء.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Nrf2 activator; inhibits Nrf2/Keap1 interaction (Kd = 6 μM). Suppresses LPS-induced iNOS and nitric oxide expression in macrophages. Anti-inflammatory.

References:
Winkel et al (2015) Characterization of RA839, a noncovalent small molecule binder to Keap1 and selective activator of Nrf2 signaling. J.Biol.Chem. 290 28446 PMID:26459563

مراجعات

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Average Rating: 5 ★★★★★ (Based on Reviews and 37 reference(s) in Google Scholar.)

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