Rebamipide (Synonyms: OPC 12759) |
رقم الكتالوجGC17367 |
ريباميبيد (OPC12759) هو عامل فعال عن طريق الفم يحمي المعدة ويعزز إنتاج PGs الذاتية (خاصة PGE2 داخل المعدة) عن طريق تحفيز تعبير COX-2 ، وبالتالي حماية الغشاء المخاطي في المعدة من الإصابة
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Cas No.: 90098-04-7
Sample solution is provided at 25 µL, 10mM.
Rebamipide (OPC12759) is a mucoprotective agent. Rebamipide induces COX-2 expression, increases PGE2 levels, and enhances gastric mucosal defense in a COX-2-dependent manner[1].
References:
[1]. Sun WH, et al. Induction of cyclooxygenase-2 in rat gastric mucosa by rebamipide, a mucoprotective agent. J Pharmacol Exp Ther. 2000 Nov;295(2):447-52.
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