الصفحة الرئيسية>>Signaling Pathways>> Proteases>> Drug Metabolite>>Regorafénib N-oxyde M2

Regorafénib N-oxyde M2

رقم الكتالوجGC33333

Regorafénib N-oxyde M2 \u200b\u200bهو مستقلب نشط من Regorafenib. Regorafenib هو مثبط متعدد الأهداف لـ VEGFR1 / 2/3 و PDGFRβ و Kit و RET و Raf-1 مع IC50s من 13 / 4.2 / 46 و 22 و 7 و 1.5 و 2.5 نانومتر ، على التوالي.

Products are for research use only. Not for human use. We do not sell to patients.

Regorafénib N-oxyde M2 التركيب الكيميائي

Cas No.: 835621-11-9

الحجم السعر المخزون الكميّة
5mg
102٫00
متوفر
10mg
167٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com

مراجعات العميل

بناء على آراء العملاء.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.

[1]. Allard M, et al. Simultaneous analysis of regorafenib and sorafenib and three of their metabolites in human plasma using LC-MS/MS. J Pharm Biomed Anal. 2017 Aug 5;142:42-48.

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