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Regorafénib N-oxyde M2

Catalog No.GC33333

Le régorafénib N-oxyde M2 \u200b\u200best un métabolite actif du régorafénib. Le régorafenib est un inhibiteur multi-cible pour VEGFR1/2/3, PDGFRβ, Kit, RET et Raf-1 avec des IC50 de 13/4,2/46, 22, 7, 1,5 et 2,5 nM, respectivement.

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Regorafénib N-oxyde M2 Chemical Structure

Cas No.: 835621-11-9

Taille Prix Stock Qté
5mg
102,00 $US
En stock
10mg
167,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.

[1]. Allard M, et al. Simultaneous analysis of regorafenib and sorafenib and three of their metabolites in human plasma using LC-MS/MS. J Pharm Biomed Anal. 2017 Aug 5;142:42-48.

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