Menin-MLL

Menin-MLL interaction is a drug target for leukemia treatment. Menin is a multiple endocrine neoplasia (MEN1) products which interacts with MLL (mixed lineage leukemia) in a histone methyltransferase complex.

منتجات لـ نبسب؛ Menin-MLL

القط. رقم اسم المنتج بيانات
GC11837 MI-136 MI-136 هو مثبط لتفاعل بروتين مينين- MLL (PPI) ، مع IC 50 من 31 نانومتر و Kd 23.6 نانومتريظهر MI-136 لمنع إشارات AR ولديه القدرة على الدراسة في الأورام المقاومة للإخصاء
GC11418 MI-2

Menin-MLL inhibitor 2;Thieno[2,3-d]pyrimidine, 4-[4-(4,5-dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-propyl-
An inhibitor of menin-MLL fusion protein interactions
GC10388 MI-2 (hydrochloride) menin-MLL interaction inhibitor
GC12199 MI-3

Menin-MLL inhibitor 3;Thieno[2,3-d]pyrimidine, 4-[4-(4,5-dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-(1-methylethyl)-
An inhibitor of menin-MLL fusion protein interactions
GC12173 MI-nc (hydrochloride) weak inhibitor of menin-MLL interaction