Resveratrol-3-O-Sulfate (sodium salt) |
| رقم الكتالوجGC44820 |
ريسفيراترول - 3 - سلفات (الصوديوم) هو مستقلب ريسفيراترول.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 858127-11-4
Sample solution is provided at 25 µL, 10mM.
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Resveratrol-3-O-sulfate is a metabolite of resveratrol . In U-937 cells stimulated with LPS, resveratrol-3-O-sulfate (1 µM) decreases the expression of IL-1α, IL-1β, and IL-6 by 61.2, 76.6, and 42.2%, respectively, and decreases the release of TNF-α and IL-6 to similar levels as resveratrol. It has antioxidant activity in a Trolox assay, dose-dependently decreases growth of Caco-2 colorectal adenocarcinoma cells when used at concentrations ranging from 10 to 100 µM, and induces apoptosis at concentrations of 25 and 50 µM. Resveratrol-3-O-sulfate also displaces rosiglitazone from the outer mitochondrial protein mitoNEET (IC50 = 3.36 µM for the human protein), indicating that it binds to the thiazolidine-2,4-dione (TZD) binding pocket.
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