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Reveromycin A

رقم الكتالوجGC41466

ريفرومايسين A ، مضاد حيوي من البنزوكوينويد معزول من جنس Streptomyces ، هو مثبط انتقائي لتخليق البروتين في الخلايا حقيقية النواة

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Reveromycin A التركيب الكيميائي

Cas No.: 134615-37-5

الحجم السعر المخزون الكميّة
250μg
483٫00
متوفر
1mg
966٫00
متوفر

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مراجعات العميل

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  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 µg/ml), displays antiproliferative activity against human KB and K562 tumor cell lines (IC50s = 1.9 and 1.6 µg/ml, respectively), and demonstrates antifungal activity against C. albicans (MIC = 2 µg/ml at pH 3). Reveromycin A also has been shown to inhibit bone resorption by inducing apoptosis in osteoclasts with an IC50 value of 0.7 µM.

مراجعات

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