Reveromycin A |
| Katalog-Nr.GC41466 |
Reveromycin A, ein aus der Gattung Streptomyces isoliertes benzochinoides Antibiotikum, ist ein selektiver Inhibitor der Proteinsynthese in eukaryotischen Zellen.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 134615-37-5
Sample solution is provided at 25 µL, 10mM.
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Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 µg/ml), displays antiproliferative activity against human KB and K562 tumor cell lines (IC50s = 1.9 and 1.6 µg/ml, respectively), and demonstrates antifungal activity against C. albicans (MIC = 2 µg/ml at pH 3). Reveromycin A also has been shown to inhibit bone resorption by inducing apoptosis in osteoclasts with an IC50 value of 0.7 µM.
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