RS 09 |
رقم الكتالوجGC50297 |
RS09 عبارة عن محاكاة ببتيد LPS تعمل كمرشح ليتم اعتباره فئة جديدة من مساعد ناهض TLR4
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Cas No.: 1449566-36-2
Sample solution is provided at 25 µL, 10mM.
TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.
Li et al (2016) Intranasal vaccination against HIV-1 with adenoviral vector-based nanocomplex using synthetic TLR-4 agonist peptide as adjuvant. Mol.Pharm. 13 885 PMID:26824411 |Shanmugam et al (2012) Synthetic Toll like receptor-4 (TLR-4) agonist peptides as a novel class of adjuvants. PLoS One 7 e30839 PMID:22363498
Average Rating: 5
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