الصفحة الرئيسية>>Proteins>> Viral Antigens>> Influenza>>(+)-Rugulosin

(+)-Rugulosin (Synonyms: NSC 160880, NSC 249990, Rugulosin A)

رقم الكتالوجGC18749

(+) -Rugulosin هي مادة تلوين بلورية من Penicillium rugulosum Thom.

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(+)-Rugulosin التركيب الكيميائي

Cas No.: 23537-16-8

الحجم السعر المخزون الكميّة
500μg
146٫00
متوفر
1mg
262٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products
(+)-Rugulosin is a pigment and mycotoxin produced by certain fungi. It inhibits HIV-1 integrase activity with IC50 values of 19 and 25 uM in coupled and strand transfer assays, respectively. It also inhibits ribonuclease H in rat liver by 83% at a concentration of 157 uM and ribonucleases H1, H2, and H3 in T. pyriformis by 100, 99, and 100%, respectively, at a concentration of 313 uM. (+)-Rugulosin leads to hepatic injury and liver cell hyperplasia in mice when administered in the diet. It is cytotoxic to insect cells but not mammalian C6/36, L929, and HepG2 cells (ID50s = 1.2, >200, 23.7, and >200 ug/ml, respectively).

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