(+)-Rugulosin (Synonyms: NSC 160880, NSC 249990, Rugulosin A) |
| カタログ番号GC18749 |
(+)-ルグロシンは、ペニシリウム ルグロサム トムの結晶色素です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 23537-16-8
Sample solution is provided at 25 µL, 10mM.
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(+)-Rugulosin is a pigment and mycotoxin produced by certain fungi. It inhibits HIV-1 integrase activity with IC50 values of 19 and 25 uM in coupled and strand transfer assays, respectively. It also inhibits ribonuclease H in rat liver by 83% at a concentration of 157 uM and ribonucleases H1, H2, and H3 in T. pyriformis by 100, 99, and 100%, respectively, at a concentration of 313 uM. (+)-Rugulosin leads to hepatic injury and liver cell hyperplasia in mice when administered in the diet. It is cytotoxic to insect cells but not mammalian C6/36, L929, and HepG2 cells (ID50s = 1.2, >200, 23.7, and >200 ug/ml, respectively).
Review for (+)-Rugulosin
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
Review for (+)-Rugulosin
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