RWJ-445167 (3DP-10017) (Synonyms: 3DP-10017) |
| رقم الكتالوجGC32567 |
RWJ-445167 (3DP-10017) (3DP-10017) هو مثبط مزدوج للثرومبين والعامل Xa مع Ki من 4.0 نانومتر و 230 نانومتر ، على التوالي ، يعرض نشاطًا قويًا مضادًا للتخثر.
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Cas No.: 226566-43-4
Sample solution is provided at 25 µL, 10mM.
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RWJ-445167 is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity.
[1]. RWJ-445167, et al. Exploration of potential prodrugs of RWJ-445167, an oxyguanidine-based dual inhibitor of thrombin and factor Xa. Chem Biol Drug Des. 2006 Jul;68(1):29-36.
Average Rating: 5 (Based on Reviews and 2 reference(s) in Google Scholar.)
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