Satralizumab |
رقم الكتالوجGC66342 |
Satralizumab هو جسم مضاد أحادي النسيلة متوافق مع البشر ، وهو مثبط قوي للإنترلوكين 6 (IL-6). يمنع Satralizumab تكوين dTAA والتقدم في rattus norvegicus. يمكن استخدام Satralizumab لاضطراب طيف التهاب النخاع والعصب البصري (NMOSD) وأبحاث تمدد الأوعية الدموية في الشريان الأورطي الصدري (dTAA).
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Cas No.: 1535963-91-7
Sample solution is provided at 25 µL, 10mM.
Satralizumab, a humanized monoclonal antibody, is a potent Interleukine-6 (IL-6) inhibitor. Satralizumab prevents dTAA formation and progression in rattus norvegicus. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research[1][2].
Satralizumab (120 mg, Subcutaneously, once every 2 weeks, for 4 weeks) prevents dTAA formation and progression in rattus norvegicus[1].
Animal Model: | Rattus norvegicus (forty, male, 10-week-old, four equal groups)[1] |
Dosage: | 120 mg |
Administration: | Subcutaneously, once every 2 weeks, for 4 weeks |
Result: | Prevented dTAA (descending thoracic aorta aneurysm) formation and progression. |
Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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