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Satralizumab

رقم الكتالوجGC66342

Satralizumab هو جسم مضاد أحادي النسيلة متوافق مع البشر ، وهو مثبط قوي للإنترلوكين 6 (IL-6). يمنع Satralizumab تكوين dTAA والتقدم في rattus norvegicus. يمكن استخدام Satralizumab لاضطراب طيف التهاب النخاع والعصب البصري (NMOSD) وأبحاث تمدد الأوعية الدموية في الشريان الأورطي الصدري (dTAA).

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Satralizumab التركيب الكيميائي

Cas No.: 1535963-91-7

الحجم السعر المخزون الكميّة
5mg
1260٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

Satralizumab, a humanized monoclonal antibody, is a potent Interleukine-6 (IL-6) inhibitor. Satralizumab prevents dTAA formation and progression in rattus norvegicus. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research[1][2].

Satralizumab (120 mg, Subcutaneously, once every 2 weeks, for 4 weeks) prevents dTAA formation and progression in rattus norvegicus[1].

Animal Model: Rattus norvegicus (forty, male, 10-week-old, four equal groups)[1]
Dosage: 120 mg
Administration: Subcutaneously, once every 2 weeks, for 4 weeks
Result: Prevented dTAA (descending thoracic aorta aneurysm) formation and progression.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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