SSR 69071 |
| رقم الكتالوجGC10672 |
A potent inhibitor of neutrophil elastase
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 344930-95-6
Sample solution is provided at 25 µL, 10mM.
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High affinity, potent inhibitor of human leukocyte elastase (HLE) (IC50 = 3.9 nM). Displays species-selectivity (Ki values are 0.017, 1.70, 3.01, 58 and > 100 nM?for human, mouse, rat, rabbit and porcine elastase respectively). Inhibits HLE-induced lung hemorrhage in mice (ID50 = 2.8 mg/kg) and reduces infarct size in an in vivo acute model of coronary ischemia-reperfusion injury. Orally active.
Review for SSR 69071
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for SSR 69071
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