SuO-Glu-Val-Cit-PAB-MMAE |
| رقم الكتالوجGC63859 |
يتكون SuO-Glu-Val-Cit-PAB-MMAE من رابط ADC قابل للانقسام (SuO-Glu-Val-Cit-PAB) ومثبط قوي لتوبيولين (MMAE)يمكن استخدام SuO-Glu-Val-Cit-PAB-MMAE في تخليق اتحادات الأجسام المضادة والأدوية (ADCs)
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1895916-24-1
Sample solution is provided at 25 µL, 10mM.
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SuO-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
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