TH 5427 hydrochloride |
| رقم الكتالوجGC50490 |
Potent NUDT5 inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2253744-57-7
Sample solution is provided at 25 µL, 10mM.
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Potent nudix hydrolase 5 (NUDT5) inhibitor (IC50 = 29 nM). Displays >650-fold selectivity for NUDT5 over MTH1. Inhibits ATP synthesis, chromatin remodeling, gene expression and proliferation in progestin-treated breast cancer cells in vitro.
Page et al (2018) Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells. Nat.Commun. 9 250 PMID:29343827
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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