Thalidomide-NH-PEG2-C2-NH2 TFA (Synonyms: Thalidomide-NH-PEG2-C2-NH2 TFA) |
| رقم الكتالوجGC38949 |
Thalidomide-NH-PEG2-C2-NH2 TFA عبارة عن اتحاد مركب ليجاند رابط مركب E3 يشتمل على رابط cereblon القائم على ثاليدوميد ورابط PEG ثنائي الوحدة المستخدم في تقنية PROTAC.
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Cas No.: 2097509-36-7
Sample solution is provided at 25 µL, 10mM.
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Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].
[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.
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