Z-FR-AMC (trifluoroacetate salt) (Synonyms: Z-FR-7-amino-4-Methylcoumarin, Z-Phe-Arg-AMC) |
| رقم الكتالوجGC49145 |
A fluorogenic substrate for cathepsin L
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Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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Z-FR-AMC is a fluorogenic substrate for cathepsin L.1 Upon enzymatic cleavage by cathepsin L, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin L activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
1.Carmona, C., Dowd, A.J., Smith, A.M., et al.Cathepsin L proteinase secreted by Fasciola hepatica in vitro prevents antibody-mediated eosinophil attachment to newly excysted juvenilesMol. Biochem. Parasitol.62(1)9-17(1993)
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