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1-Arachidoyl Lysophosphatidic Acid (sodium salt) (Synonyms: 1-Arachidoyl LPA; 1-Eicosanoyl-Lysophosphatidic Acid; LPA(20:0))

Catalog No.GC91429 Copy One-Click Copy Product Info

1-El ácido lisofosfatídico araquidilo (1-arachidoyl LPA) es un agonista del receptor de ácido lisofosfatídico 1 (LPA1) y un glicerofosfolípido que contiene ácido araquídico en la posición sn-1.

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1-Arachidoyl Lysophosphatidic Acid (sodium salt) Chemical Structure

Tamaño Precio Disponibilidad Cantidad
1mg
136,00 $
Disponible
5mg
612,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.



Description of 1-Arachidoyl Lysophosphatidic Acid (sodium salt)

1-Arachidoyl lysophosphatidic acid (1-arachidoyl LPA) is an agonist of lysophosphatidic acid receptor 1 (LPA1) and a glycerophospholipid containing arachidic acid at the sn-1 position.1 It induces calcium mobilization in primary human lung fibroblasts (EC50 = 3.6 µM), which endogenously express LPA1 but not LPA2-LPA6. 1-Arachidoyl LPA (2.5 µM) also binds to the ligand-binding domain of peroxisome proliferator-activated receptor γ (PPARγ) in a cell-free assay.2 It has been found in human urine.3

Chemical Properties of 1-Arachidoyl Lysophosphatidic Acid (sodium salt)

Cas No. SDF
Sinónimos 1-Arachidoyl LPA; 1-Eicosanoyl-Lysophosphatidic Acid; LPA(20:0)
Formula C23H46O7P • Na M.Wt 488.6
Solubility Methanol: Soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 1-Arachidoyl Lysophosphatidic Acid (sodium salt)

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1 mg 5 mg 10 mg
1 mM 2.0467 mL 10.2333 mL 20.4666 mL
5 mM 409.3 μL 2.0467 mL 4.0933 mL
10 mM 204.7 μL 1.0233 mL 2.0467 mL
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In vivo Formulation Calculator (Clear solution) of 1-Arachidoyl Lysophosphatidic Acid (sodium salt)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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