1-Arachidoyl Lysophosphatidic Acid (sodium salt) (Synonyms: 1-Arachidoyl LPA; 1-Eicosanoyl-Lysophosphatidic Acid; LPA(20:0)) |
Catalog No.GC91429 |
1-El ácido lisofosfatídico araquidilo (1-arachidoyl LPA) es un agonista del receptor de ácido lisofosfatídico 1 (LPA1) y un glicerofosfolípido que contiene ácido araquídico en la posición sn-1.
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Sample solution is provided at 25 µL, 10mM.
1-Arachidoyl lysophosphatidic acid (1-arachidoyl LPA) is an agonist of lysophosphatidic acid receptor 1 (LPA1) and a glycerophospholipid containing arachidic acid at the sn-1 position.1 It induces calcium mobilization in primary human lung fibroblasts (EC50 = 3.6 µM), which endogenously express LPA1 but not LPA2-LPA6. 1-Arachidoyl LPA (2.5 µM) also binds to the ligand-binding domain of peroxisome proliferator-activated receptor γ (PPARγ) in a cell-free assay.2 It has been found in human urine.3
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