1-Ethynylpyrene |
| Catalog No.GC60446 |
El 1-etinilpireno es un inhibidor arilacetilénico de los citocromos P450 1A1, 1A2 y 2B1 con IC50 de 0,18, 0,32 y 0,04 μM, respectivamente.
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Cas No.: 34993-56-1
Sample solution is provided at 25 µL, 10mM.
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1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1, 1A2, and 2B1 with IC50s of 0.18, 0.32, and 0.04 μM, respectively[1].
1-Ethynylpyrene exhibits activity against P450 1A2, and 2B1 with Kis of 0.32 and 0.04 μM, respectively[1].
[1]. Naijue Zhu, et al. Ethynyl and Propynylpyrene Inhibitors of Cytochrome P450. J Chem Crystallogr. 2010 Apr 1;40(4):343-352.
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