2-Di-1-ASP |
Catalog No.GC38730 |
2-Di-1-ASP (Compuesto 18a) es un colorante de monoestrilo y se usa ampliamente como tinciÓn mitocondrial y sondas fluorescentes de uniÓn al surco para ADN de doble cadena.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2156-29-8
Sample solution is provided at 25 µL, 10mM.
2-Di-1-ASP (Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA[1].
2-Di-1-ASP (Compound 18a) displays significant fluorescence enhancements in the presence of G-quadruplex (G4) structures (up to 300-fold), and good selectivity with respect to double-stranded DNA. 2-Di-1-ASP shows fluorimetric selectivity for parallel G4-DNA forms (c-kit2, c-kit87up, c-myc)[1].
[1]. Xie X, et al. Identification of optimal fluorescent probes for G-quadruplex nucleic acids through systematic exploration of mono- and distyryl dye libraries. Beilstein J Org Chem. 2019 Aug 6;15:1872-1889.
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