3-Bromotyrosine-13C9,15N (trifluoroacetate salt) (Synonyms: 3-bromo-Tyr-13C9,15N) |
Catalog No.GC42252 |
3-Bromotyrosine-13C9,15N is intended for use as an internal standard for the quantification of 3-bromotyrosine by GC- or LC-MS.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
3-Bromotyrosine-13C9,15N is intended for use as an internal standard for the quantification of 3-bromotyrosine by GC- or LC-MS. 3-Bromotyrosine is a product of protein oxidation found after activation of eosinophils during an allergic response. It has been used as a marker of eosinophil peroxidase-induced protein oxidation in vitro and in vivo. In addition to its production in eosinophils, 3-bromotyrosine is found at 5-fold higher levels in peritoneal exudate from mice infected with K. pneumoniae compared with uninfected animals, suggesting neutrophils release higher levels of oxidized products during inflammation. In a human study, 3-bromotyrosine was increased in allergen-challenged lung samples from subjects with allergen-induced asthma.
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