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A40926

Catalog No.GC62002 Copy One-Click Copy Product Info

A40926, el precursor de Dalbavancin, es un antibiÓtico glicopéptido de segunda generaciÓn.

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A40926 Chemical Structure

Cas No.: 102961-72-8

Tamaño Precio Disponibilidad Cantidad
5 mg
135,00 $
Disponible
10 mg
216,00 $
Disponible
25 mg
450,00 $
Disponible
50 mg
666,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.



Description of A40926

A40926, the precursor of Dalbavancin, is a second-generation glycopeptide antibiotic. A40926 inhibits gram-positive bacteria, and is very active against Neisseria gonorrhoeae[1].

[1]. Goldstein BP, et al. A40926, a new glycopeptide antibiotic with anti-Neisseria activity.Antimicrob Agents Chemother. 1987 Dec;31(12):1961-6.

Chemical Properties of A40926

Cas No. 102961-72-8 SDF
Canonical SMILES OC([C@](NC([C@](N1)([H])[C@@H](C2=CC=C(OC3=C(O[C@H]4[C@@H]([C@H]([C@H](O)[C@@H](C(O)=O)O4)O)NC(CCCCCCC(C)C)=O)C5=CC([C@](NC([C@](N6)([H])C7=C(Cl)C(O)=CC(OC8=C(O)C=CC([C@@H](NC)C(N[C@@](CC9=CC=C(O5)C=C9)([H])C6=O)=O)=C8)=C7)=O)([H])C(N[C@@]%10([H])C1=O)=O)=C3)C(Cl)=C2)O)=O)([H])C%11=CC(O)=CC(O[C@H]%12O[C@@H]([C@@H](O)[C@H](O)[C@@H]%12O)COC(C)=O)=C%11C%13=CC%10=CC=C%13O)=O
Formula C83H86Cl2N8O30 M.Wt 1746.51
Solubility DMSO : 5.88 mg/mL (3.39 mM; ultrasonic and warming and heat to 20°C) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of A40926

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 572.6 μL 2.8629 mL 5.7257 mL
5 mM 114.5 μL 572.6 μL 1.1451 mL
10 mM 57.3 μL 286.3 μL 572.6 μL
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In vivo Formulation Calculator (Clear solution) of A40926

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for A40926

Average Rating: 5 ★★★★★ (Based on Reviews and 22 reference(s) in Google Scholar.)

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