Adomeglivant (LY2409021) (Synonyms: LY2409021) |
| Catalog No.GC31322 |
Adomeglivant (LY2409021) (LY2409021) es un antagonista alostérico potente y selectivo del receptor de glucagÓn (GluR).
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Cas No.: 1488363-78-5
Sample solution is provided at 25 µL, 10mM.
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Adomeglivant is a potent and selective glucagon receptor antagonist that is used in clinical trial for type 2 diabetes mellitus.
[1]. Li Y et al. Efficient Synthesis of β-CF3/SCF3-Substituted Carbonyls via Copper-Catalyzed Electrophilic Ring-Opening Cross-Coupling of Cyclopropanols. Org Lett. 2015 May 1;17(9):2186-9. [2]. Kazda CM et al. Evaluation of Efficacy and Safety of the Glucagon Receptor Antagonist LY2409021 in Patients With Type 2 Diabetes: 12- and 24-Week Phase 2 Studies. Diabetes Care. 2016 Jul;39(7):1241-9.
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