Berberine ursodeoxycholate (Synonyms: HTD1801; BUDCA) |
Catalog No.GC66456
One-Click Copy Product Info
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El ursodesoxicolato de berberina (HTD1801), una sal iÓnica de berberina y Ácido ursodesoxicÓlico, es un agente hipolipidémico potente y activo por vÍa oral. El ursodesoxicolato de berberina muestra una reducciÓn significativamente grande en el contenido de grasa del hÍgado. El ursodesoxicolato de berberina tiene un amplio espectro de actividad metabÓlica. El ursodesoxicolato de berberina se puede utilizar para la investigaciÓn de la hiperlipidemia, la esteatohepatitis no alcohÓlica (EHNA) y la diabetes.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1868138-66-2
Sample solution is provided at 25 µL, 10mM.
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Berberine ursodeoxycholate (HTD1801), an ionic salt of Berberine and Ursodeoxycholic acid, is an orally active and potent hypolipidemic agent. Berberine ursodeoxycholate shows significantly great reduction in liver fat content. Berberine ursodeoxycholate has a broad spectrum of metabolic activity. Berberine ursodeoxycholate can be used for the research of hyperlipidemia, non-alcoholic steatohepatitis (NASH) and diabetes[1][2].
Berberine ursodeoxycholate shows significant reductions in HbA1c (hemoglobin A1c) levels, mean HbA1c levels decreases by 0.6%[1].
Berberine ursodeoxycholate is ingested in the form of a salt and it is thought that the salt promptly dissociates within the gastrointestinal tract and that Berberine and Ursodeoxycholic acid are differentially absorbed[1].
| Cas No. | 1868138-66-2 | SDF | |
| Sinónimos | HTD1801; BUDCA | ||
| Formula | C44H57NO8 | M.Wt | 727.93 |
| Solubility | DMSO : 5 mg/mL (6.87 mM; ultrasonic and warming and heat to 60°C) | Storage | 4°C, away from moisture and light |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 1.3738 mL | 6.8688 mL | 13.7376 mL |
| 5 mM | 274.8 μL | 1.3738 mL | 2.7475 mL |
| 10 mM | 137.4 μL | 686.9 μL | 1.3738 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)