Captan (Synonyms: NSC 36726) |
Catalog No.GC47035
One-Click Copy Product Info
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Captan es un fungicida agrÍcola comÚn utilizado para controlar Botrytis, Fusarium, Fusicoccum, Pythium.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 133-06-2
Sample solution is provided at 25 µL, 10mM.
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Captan is a trichloromethyl sulfenyl fungicide that degrades into thiophosgene, a highly reactive compound that reacts with thiol and non-thiol proteins, in cells.1 It reduces radial growth of and starch depletion by A. fumigatus on the leaf surface of A. tenuis when used at a concentration of 50 μg/ml.2 Captan (50-1,000 mg/kg) increases the number of micronuclei and chromosomal aberrations in polychromatic erythrocytes in bone marrow in mice.3 It also induces chromosomal aberrations in spermatocytes and sperm head abnormalities in mice. Captan reduces survival of adult male and female alfalfa leafcutting bees (M. rotunda) when applied topically or administered in the diet at concentrations of 150-684 and 24.45-48.9 g/L, respectively.4
1.Long, J.W., and Siegel, M.R.Mechanism of action and fate of the fungicide chlorothalonil (2,4,5,6-tetrachloroisophthalonitrile) in biological systems. 2. In vitro reactionsChem. Biol. Interact.10(6)383-394(1975) 2.Kithubutheen, A.J., and Pugh, G.J.Effects of fungicides on Aspergillus fumigatusAntonie Van Leeuwenhoek45(2)303-312(1979) 3.Feng, J.Y., and Lin, B.Y.Cytogenetic effects of an agricultural antibiotic, captan, on mouse bone marrow and testicular cellsEnviron. Res.43(2)359-363(1987) 4.Huntzinger, C.I., James, R.R., Bosch, J., et al.Fungicide tests on adult alfalfa leafcutting bees (Hymenoptera: Megachilidae)J. Econ. Entomol.101(4)1088-1094(2008)
| Cas No. | 133-06-2 | SDF | |
| Sinónimos | NSC 36726 | ||
| Canonical SMILES | O=C1N(SC(Cl)(Cl)Cl)C(C2CC=CCC21)=O | ||
| Formula | C9H8Cl3NO2S | M.Wt | 300.6 |
| Solubility | DMSO : 50 mg/mL (166.34 mM; Need ultrasonic) | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 3.3267 mL | 16.6334 mL | 33.2668 mL |
| 5 mM | 665.3 μL | 3.3267 mL | 6.6534 mL |
| 10 mM | 332.7 μL | 1.6633 mL | 3.3267 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)