Bacitracin Complex

Name: Bacitracin Complex
Brand: GlpBio
SKU: GC46905
Availability: InStock
Rating: 5 (32 reviews)

Catalog No.GC46905

A mixture of bacitracin polypeptides in complex with copper

Products are for research use only. Not for human use. We do not sell to patients.

Bacitracin Complex Chemical Structure

Cas No.: N/A

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Cantidad

25 mg	153,00 $	Disponible
100 mg	488,00 $	Disponible

Tel：(909) 407-4943 Email: sales@glpbio.com

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Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.

GlpBio Products Cited In Reputable Papers

Nature
610.7931 (2022): 366-372

Nature
618, 1017–1023 (2023)

Cell
183.7 (2020): 1867-1883

Cell Research
31, 1291–1307 (2021)

Cell Research
33, 273–287 (2023)

Cell Research
33, 546–561 (2023)

Molecular Cancer
21.1 (2022): 1-17

Molecular Cancer
21.1 (2022): 1-18

Cancer Cell
39 (2021): 1-16

Cell Host Microbe
30.8 (2022): 1124-1138

Cell Host Microbe
31.5 (2023): 766-780

Cell Host Microbe
31.3 (2023): 418-43

Cell Metabolism
34.2 (2022): 240-255

Ann Rheum Dis
82(4): 533-545 (2023)

Cell Mol Immunol
20, 264–276 (2023)

Adv Funct Mater
33.35 (2023): 2214998

Description Chemical Properties Product Documents

Product Documents

Quality Control & SDS

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Purity: >95.00%

Bacitracin complex is a bacitracin antibiotic complex composed of cyclic dipeptides that has been found in Bacillus.¹ It is metal-dependent and is complexed to a divalent metal cation, such as Cu²⁺, Ni²⁺, Co²⁺, Zn²⁺, or Mn²⁺, for its activity.^1,2 Bacitracin complex is a mixture of bacitracin polypeptides in complex with copper.

1.Piacham, T., Isarankura-Na-Ayudhya, C., Nantasenamat, C., et al.Metalloantibiotic Mn(II)-bacitracin complex mimicking manganese superoxide dismutaseBiochem. Biophys. Res. Commun.341(4)925-930(2006) 2.RodrÍguez-Uribe, N.A., PÉrez-GonzÁlez, R., DomÍnguez-Mendoza, B.E., et al.Metallobacitracins: Affinity and structural study in aqueous solutionInorg. Chem. Commun.10461-70(2019)

Cas No.	N/A	SDF
Canonical SMILES	O=C1N[C@@H](CC(N)=O)C(NCCCC[C@@H](C(N[C@@H](C(N[C@@]([H])([C@@H](C)CC)C(N[C@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@@H]1CC([O-])=O)=O)CC3=CN=CN3)=O)=O)=O)CCCN)=O)NC([C@@]([C@@H](C)CC)([H])NC([C@@H](CCC([O-])=O)NC([C@H](CC(C)C)NC([C@@H]4CSC([C@@H](N)[C@@H](C)CC)=N4)=O)=O)=O)=O)=O.O=C5N[C@@H](CC(N)=O)C(NCCCC[C@@H](C(N[C@@H](C(N[C@@]([H])([C@@H](C)CC)C(N[C@H](CC6=CC=CC=C6)C(N[C@H](C(N[C@@H]5CC([O-])=O)=O)CC7=CN=CN7)=O)=O)=O)CCCN)=O)NC([C@@]([C@@H](C)CC)([H])NC([C@@H](CCC([O-])=O)NC([C@H](CC(C)C)NC([C@@H]8CSC([C@@H](N)C(C)C)=N8)=O)=O)=O)=O)=O.O=C9N[C@@H](CC(N)=O)C(NCCCC[C@@H](C(N[C@@H](C(N[C@@]([H])(C(C)C)C(N[C@H](CC%10=CC=CC=C%10)C(N[C@H](C(N[C@@H]9CC([O-])=O)=O)CC%11=CN=CN%11)=O)=O)=O)CCCN)=O)NC([C@@]([C@@H](C)CC)([H])NC([C@@H](CCC([O-])=O)NC([C@H](CC(C)C)NC([C@@H]%12CSC([C@@H](N)[C@@H](C)CC)=N%12)=O)=O)=O)=O)=O.O=C%13N[C@@H](CC(N)=O)C(NCCCC[C@@H](C(N[C@@H](C(N[C@@]([H])([C@@H](C)CC)C(N[C@H](CC%14=CC=CC=C%14)C(N[C@H](C(N[C@@H]%13CC([O-])=O)=O)CC%15=CN=CN%15)=O)=O)=O)CCCN)=O)NC([C@@](C(C)C)([H])NC([C@@H](CCC([O-])=O)NC([C@H](CC(C)C)NC([C@@H]%16CSC([C@@H](N)[C@@H](C)CC)=N%16)=O)=O)=O)=O)=O.O=C%17N[C@@H](CC(N)=O)C(NCCCC[C@@H](C(N[C@@H](C(N[C@@]([H])(C(C)C)C(N[C@H](CC%18=CC=CC=C%18)C(N[C@H](C(N[C@@H]%17CC([O-])=O)=O)CC%19=CN=CN%19)=O)=O)=O)CCCN)=O)NC([C@@]([C@@H](C)CC)([H])NC([C@@H](CCC([O-])=O)NC([C@H](CC(C)C)NC([C@@H]%20CSC([C@@H](N)C(C)C)=N%20)=O)=O)=O)=O)=O.O=C%21N[C@@H](CC(N)=O)C(NCCCC[C@@H](C(N[C@@H](C(N[C@@]([H])([C@@H](C)CC)C(N[C@H](CC%22=CC=CC=C%22)C(N[C@H](C(N[C@@H]%21CC([O-])=O)=O)CC%23=CN=CN%23)=O)=O)=O)CCCN)=O)NC([C@@](C(C)C)([H])NC([C@@H](CCC([O-])=O)NC([C@H](CC(C)C)NC([C@@H]%24CSC([C@@H](N)C(C)C)=N%24)=O)=O)=O)=O)=O.O=C%25N[C@@H](CC(N)=O)C(NCCCC[C@@H](C(N[C@@H](C(N[C@@]([H])(C(C)C)C(N[C@H](CC%26=CC=CC=C%26)C(N[C@H](C(N[C@@H]%25CC([O-])=O)=O)CC%27=CN=CN%27)=O)=O)=O)CCCN)=O)NC([C@@](C(C)C)([H])NC([C@@H](CCC([O-])=O)NC([C@H](CC(C)C)NC([C@@H]%28CSC([C@@H](N)[C@@H](C)CC)=N%28)=O)=O)=O)=O)=O.O=C%29N[C@@H](CC(N)=O)C(NCCCC[C@@H](C(N[C@@H](C(N[C@@]([H])(C(C)C)C(N[C@H](CC%30=
Formula	C66H101N17O16S.Cu (for A)	M.Wt	1484.2
Solubility		Storage	Store at -20°C
General tips	Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition	Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
		1 mg	5 mg	10 mg
	1 mM	0.6738 mL	3.3688 mL	6.7376 mL
	5 mM	0.1348 mL	0.6738 mL	1.3475 mL
	10 mM	0.0674 mL	0.3369 mL	0.6738 mL

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO + % + % Tween 80 + % ddH₂O

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 32 reference(s) in Google Scholar.)

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