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Carviolin

Catalog No.GC47046

La carviolina es un compuesto aislado del micelio del ascomiceto Neobulgaria pura.

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Carviolin Chemical Structure

Cas No.: 478-35-3

Tamaño Precio Disponibilidad Cantidad
1 mg
472,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

Carviolin is an anthraquinone fungal metabolite that has been found in Z. longicaudata with immunosuppressive and antitrypanosomal activities.1,2 It inhibits LPS- or concanavalin A-induced proliferation of mouse splenocytes (IC50s = 4 and 4.5 µg/ml, respectively).1 Carviolin is active against T. b. brucei (MIC = 41.66 µM).2

1.Fujimoto, H., Nakamura, E., Okuyama, E., et al.Six immunosuppressive features from an ascomycete, Zopfiella longicaudata, found in a screening study monitored by immunomodulatory activityChem. Pharm. Bull. (Tokyo)52(8)1005-1008(2004) 2.Aly, A.H., Debbab, A., Clements, C.M., et al.NF kappa B inhibitors and antitrypanosomal metabolites from endophytic fungus Penicillium sp. isolated from Limonium tubiflorumBioorg. Med. Chem.19(1)414-421(2011)

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Average Rating: 5 ★★★★★ (Based on Reviews and 36 reference(s) in Google Scholar.)

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