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pNPS-DHA (Synonyms: CAY10741, Compound 59, DHA-nitrophenyl sulfonamide, p-Nitrophenyl sulfonamide Docosahexaenoic Acid)

Catalog No.GC47964

An anti-allergic DHEA derivative

Products are for research use only. Not for human use. We do not sell to patients.

pNPS-DHA Chemical Structure

Cas No.: 2454246-25-2

Tamaño Precio Disponibilidad Cantidad
1 mg
43,00 $
Disponible
5 mg
128,00 $
Disponible
10 mg
237,00 $
Disponible
25 mg
536,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

pNPS-DHA is an arylamide derivative of docosahexaenoyl ethanolamide that has anti-allergic activity.1 It inhibits degranulation of RBL-2H3 mast cells (IC50 = 15 µM). pNPS-DHA (1,000 mg/kg) inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) in mice.

1.Kim, I.-H., Kanayama, Y., Nishiwaki, H., et al.Structure-activity relationships of fish oil derivatives with anti-allergic activity in vitro and in vivoJ. Med. Chem.62(21)9576-9592(2019)

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Average Rating: 5 ★★★★★ (Based on Reviews and 18 reference(s) in Google Scholar.)

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