PCL 016 |
| Catalog No.GC32372 |
PCL 016 es un agente antiviral tÓpico que inhibe la replicaciÓn de adenovirus en conejos.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 98-98-6
Sample solution is provided at 25 µL, 10mM.
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PCL 016 is a topical antiviral agent, which inhibits adenovirus replication in rabbit.
Topical 1.5% PCL, 0.8% PCL, 0.369% PCL (pH7), 0.369% PCL (pH4) and 0.5% CDV are significantly more effective than the Control in reducing Ad Positive Cultures/Total (Days 1-14) and the Duration of Ad Shedding in the Ad5/NZW rabbit ocular model. Although not statistically significant, there appears to be a trend toward concentration-dependent efficacy of PCL 016 on the Duration of Ad Shedding. There is no apparent ocular toxicity associated with PCL 016 concentrations[1].
[1]. E.G. Romanowski, et al. A Novel Topical Antiviral Agent, PCL-016 (Picolinic Acid), Inhibits Adenovirus Replication in the Ad5/NZW Rabbit Ocular Model. ARVO Annual Meeting Abstract. May 2005 Volume 46, Issue 13.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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