Taurohyodeoxycholic Acid |
Catalog No.GC41562 |
El Ácido taurohiodesoxicÓlico es la forma tauroconjugada del Ácido hipodesoxicÓlico (HDCA, un Ácido biliar natural dihidroxilado).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2958/4/5
Sample solution is provided at 25 µL, 10mM.
Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid . THDCA decreases the size and weight of human gallstones in vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats. Co-administration of THDCA with taurochenodeoxycholic acid prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats. THDCA also reduces myeloperoxidase activity, expression of TNF-α and IL-6, and colonic damage in a mouse model of TNBS-induced ulcerative colitis.
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