- Cat.No. Nombre del producto Información
- GC18498 Cathepsin L Inhibitor El inhibidor de catepsina L (Z-Phe-Tyr-CHO) es un inhibidor potente y especÍfico de catepsina L (CTSL).
- GC68023 HIV-1 inhibitor-48
- GC65158 HIV-1 inhibitor-8 El inhibidor 8 del VIH-1 es un inhibidor de la transcriptasa inversa no nucleÓsido (NNRTI) del VIH-1 activo por vÍa oral, de baja toxicidad y potente.
- GC68449 CA inhibitor 1
- GC40724 Heat Shock Protein Inhibitor II Heat shock protein (Hsp) inhibitor II is the active form of Hsp inhibitor I and a benzylidene lactam compound that prevents the synthesis of inducible Hsps, such as Hsp105, Hsp72, and Hsp40.
- GC65256 HIV-1 inhibitor-6 El inhibidor 6 del VIH-1 (compuesto 9), un compuesto a base de diheteroarilamida, es un potente inhibidor alternativo del corte y empalme del pre-ARNm del VIH-1.
- GC48985 NF-κB Inhibitor (trifluoroacetate salt) A cell-permeable peptide that blocks nuclear import of NF-κB
- GC52334 ENPP1 Inhibitor 4e An ENPP1 inhibitor
- GC47708 MPro Inhibitor 11b MPro Inhibitor 11b es un inhibidor covalente del SARS-CoV-2 3CLpro, con una IC50 de 40 nM.
- GC47707 MPro Inhibitor 11a An inhibitor of SARS-CoV-2 Mpro
-
GC43894
IKK2 Inhibitor VI
Inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling.
- GC49430 Wee1 Inhibitor Wee1 Inhibitor es un potente inhibidor de la quinasa Wee1 del punto de control con un IC50 de 0,011 μM.
- GC40922 SRS11-92 SRS11-92, un anÁlogo de Ferrostatin-1 (Fer-1), es un potente inhibidor de la ferroptosis.
- GC52315 GK241 An sPLA2 (Type IIA) inhibitor
- GC52272 Jun9-72-2 A SARS-CoV-2 PLpro inhibitor
- GC52240 BPH-1358 An inhibitor of UPPS and FPPS
- GC49915 Hexa-D-Arginine (trifluoroacetate salt) A furin inhibitor
- GC49265 PKI (14-22) amide (myristoylated) (trifluoroacetate salt) A PKA inhibitor
- GC49144 NAG-thiazoline An OGA inhibitor
- GC49139 CAY10784 A STAT3 inhibitor
- GC49079 C82 An Mtb CdnP inhibitor
- GC48464 GC376 (sodium salt) An inhibitor of 3C- and 3C-like proteases
- GC48439 IMP-1700 An inhibitor of bacterial DNA repair
- GC48101 SSAA09E1 A SARS-CoV entry inhibitor
- GC47805 N-Phenylthiourea A tyrosinase inhibitor and building block
- GC47129 CU-76 A cGAS inhibitor
- GC47128 CU-32 A cGAS inhibitor
- GC46984 C-171 C-171 es un inhibidor del estimulador de genes de interferÓn (STING).
- GC46983 C-170 C-170 (C-170) es un inhibidor de STING potente y covalente.
- GC46895 Aurintricarboxylic Acid (ammonium salt) A protein synthesis inhibitor with diverse biological activities
- GC46883 AS-2077715 An inhibitor of fungal complex III
- GC46840 Amicoumacin B An amicoumacin with quorum-sensing inhibitory activity
- GC61002 Lomibuvir Lomibuvir (VX-222), un inhibidor selectivo de la polimerasa no nucleÓsido, se dirige al bolsillo 2 del pulgar de la polimerasa NS5B del VHC (RdRp) con una Kd de 17 nM.
- GC45995 DO264 An ABHD12 inhibitor
- GC45251 (-)-Neplanocin A S-Adenosylhomocysteine (SAH) hydrolase catalyzes the reversible hydrolysis of SAH to adenosine and homocysteine.
- GC45174 YM-53601 YM-53601, un inhibidor de la escualeno sintasa, reduce los niveles de colesterol y triglicéridos en plasma in vivo .
- GC45110 UCM53 An inhibitor of bacterial cell division
- GC45012 Tenofovir diphosphate (sodium salt) Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM).
- GC44948 StA-IFN-1 StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1, which specifically inhibits the IKKβ component of the IFN induction pathway.
- GC44891 Simeprevir (sodium salt) El simeprevir (TMC435; TMC435350) sÓdico es un inhibidor de la proteasa NS3/4A del virus de la hepatitis C (VHC) oral, potente y altamente especÍfico con una Ki de 0,36 nM.
- GC44880 SD 1029 SD 1029 es un inhibidor de JAK2/STAT3. SD 1029 inhibe la translocación nuclear STAT3. SD 1029 es un inhibidor de la activación de STAT3 debido a la inhibición de la fosforilación de JAK2.
- GC44388 NF-κB Control NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.
-
GC44241
Moenomycin Complex
Moenomycin complex is a mixture of moenomycins A, A12, C1, C3 and C4, which are antibiotics isolated from several strains of Streptomyces that directly inhibit bacterial peptidoglycan glycosyltransferases.
- GC43893 iKIX1 iKIX1 es un agente antifÚngico y vuelve a sensibilizar a C.
- GC43883 Hymeglusin La himeglusina, como antibiÓtico fÚngico de β-lactona, es un inhibidor de la HMG-CoA sintasa (IC50 = 0,12 μM).
- GC43773 Glyburide (potassium salt) Glyburide is a sulfonylurea and an inhibitor of sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 (IC50 = 4.3 nM).
- GC43368 D,L-1′-Acetoxychavicol Acetate D,L-1′-Acetoxychavicol acetate is a natural compound first isolated from the rhizomes of ginger-like plants.
- GC43196 CAY10704 CAY10704 is a potent inhibitor of hepatitis C virus (HCV) infection (EC50 = 17 nM) that displays low cytotoxicity of virally-infected human hepatoma Huh7.5.1 cells (CC50 = 21.3 μM).
- GC43176 CAY10575 CAY10575 (Compuesto 8) es un inhibidor de IKK2 con un IC50 de 0,075 μM.
- GC43143 Cardanol triene Cardanol triene is a phenol found in cashew nut shell liquid that reversibly inhibits tyrosinase with an IC50 value of 40.5 μM in vitro.
- GC43142 Cardanol diene Cardanol diene is a phenol found in cashew nut shell liquid that inhibits tyrosinase with an IC50 value of 52.5 μM in vitro.
- GC42953 BMS 345541 (trifluoroacetate salt) BMS 345541 is a cell permeable inhibitor of the IκB kinases IKKα and IKKβ (IC50s = 4 and 0.3 μM).
- GC42943 Bischloroanthrabenzoxocinone Bacterial type II fatty acid synthesis (FAS-II) is mediated by a series of enzymes, each of which may be targeted by potential antibiotics.
- GC42880 Avenanthramide-C methyl ester Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM).
- GC42780 Ambuic Acid Ambuic acid is a cyclohexanone originally isolated from Pestalotiopsis and Monochaetia species that has phytopathogenic antifungal, quorum sensing inhibitory, and antibacterial activities.
- GC41281 2'-C-Methyladenosine 2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication (IC50 = 0.3 μM in Huh-7 human hepatoma cells) that is not cytotoxic at concentrations up to 100 μM.
- GC41251 Pirlindole El pirlindol es un inhibidor de la MAO-A selectivo y reversible.
- GC40569 Cyclopenin La ciclopenina (ciclopenina) es el enantiómero de la ciclopenina.
- GC40294 D-Eritadenine D-Eritadenine is an adenosine analog and a potent, reversible inhibitor of S-adenosylhomocysteine hydrolase (SAAH; IC50 = 7 nM).
- GC40101 IMP-1088 IMP-1088 es un potente inhibidor dual humano de N-miristoiltransferasas NMT1 y NMT2 con IC50 de <1 nM para HsNMT1 y HsNMT2.
- GC19001 Tetromycin B Tetromycin B is a cysteine protease inhibitor with Ki values of 0.62, 1.42, 32.5, and 1.59 μM for rhodesain, falcipain-2, cathepsin L, and cathepsin B, respectively.
- GC18782 CAY10657 The NF-κB/Rel family of transcription factors induce and coordinate the expression of pro-inflammatory genes including cytokines, chemokines, interferons, MHC proteins, growth factors, and cell adhesion molecules.
- GC18751 Reticulol Reticulol is an isocoumarin derivative produced by certain species of Streptomyces that inhibits cAMP phosphodiesterase (IC50 = 41 uM).
- GC18699 JCP174 JCP174 es un inhibidor de la palmitoil proteÍna tioesterasa-1 (TgPPT1), una depalmitoilasa del parÁsito T.
- GC18510 Siccanin Siccanin is an inhibitor of mitochondrial complex II (succinate dehydrogenase; IC50s = 0.87 and 9.3 μM for P.
- GC18449 Cardanol monoene El cardanol monoeno (Cardanol C15:1) es un compuesto fenÓlico que se puede encontrar en el lÍquido de la cÁscara de la nuez de la India. El cardanol monoeno puede inducir la apoptosis asociada a las mitocondrias en células de melanoma humano.
- GC18443 Acetyl-6-formylpterin Acetyl-6-formylpterin is an inhibitor of mucosal-associated invariant T (MAIT) cell activation.
- GC18322 CAY10567 Akt1, 2, and 3 are serine/threonine protein kinases in the phosphatidylinositol 3 (PI3)-kinase signalling pathway that play a critical role in the regulation of cell proliferation and survival.
-
GC18298
Virstatin
Virstatin es un inhibidor del regulador transcripcional ToxT de V.
- GC18191 Elastatinal Elastatinal es un inhibidor potente y competitivo de la elastasa, con una Ki de 0,21 μM.