- Cat.No. Nombre del producto Información
- GC40048 MPS1/TTK Inhibitor MPS1/TTK inhibitor is an inhibitor of monopolar spindle 1 (MPS1/TTK; IC50 = 5.8 nM), a kinase involved in mitotic spindle checkpoint signaling that is overexpressed in certain cancerous tumors.
- GC25075 Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222) Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222, Antibiotic C 15003P3) is a potent inhibitor of tubulin polymerization with IC50 of 3.4 μM.
- GC49404 Paclitaxel C A taxoid and an inhibitor of microtubule depolymerization
- GC48423 19-O-Acetylchaetoglobosin A La 19-O-acetilquetoglobosina A, un alcaloide del citocalasano, es un metabolito fÚngico aislado originalmente de C. globosum que tiene actividades inhibidoras de la polimerizaciÓn de actina y citotÓxicas. La 19-O-acetilquetoglobosina A es citotÓxica para las células de cÁncer de cuello uterino HeLa.
- GC48394 Phomopsinamine An inhibitor of microtubule polymerization
- GC48119 Suprafenacine An inhibitor of tubulin polymerization with anticancer activity
- GC43469 Diminutol Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis.
- GC42933 Binucleine 2 Binucleine 2 is an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki = 0.36 μM), a kinase involved in cell division.
- GC41739 (S)-nitro-Blebbistatin (S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases.
- GC41564 MPT0B014 An inhibitor of tubulin polymerization
- GC41557 (S)-3'-amino Blebbistatin (S)-3'-amino Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases.
- GC41484 (S)-3'-hydroxy Blebbistatin (S)-3'-hydroxy Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases.
- GC40890 CAY10701 CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively).
- GC40664 Colcemid Colcemid es una inhibición de citoesqueleto, cuando las células de mamíferos y los ovocitos inducen la detención mitótica o la detención meiótica respectivamente durante la fase de ruptura de la vesícula.
- GC18578 YK-3-237 YK-3-237, un activador de SIRT1, se dirige al mutante p53. YK-3-237 inhibe la proliferaciÓn de células de cÁncer de mama triple negativas.
- GC18445 N-Deacetylcolchicine An inhibitor of microtubule polymerization