- Cat.No. Nombre del producto Información
- GC45770 Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092 An inhibitor of hematopoietic-type PGDS
- GC52516 Erbstatin A tyrosine kinase inhibitor
- GC48447 TAS 205 An inhibitor of H-PGDS
- GC47528 Ketorolac (calcium salt) El ketorolaco (RS37619) hemicÁlcico es un fÁrmaco antiinflamatorio no esteroideo (AINE) que actÚa como un inhibidor no selectivo de la COX, con IC50 de 20 nM para COX-1 y 120 nM para COX-2.
- GC47287 Eltenac Eltenac, un fÁrmaco antiinflamatorio no esteroideo (AINE), es un inhibidor de la COX.
- GC46682 5-Butyl-4-[2,3-difluoro-4-(phenylmethoxy)phenyl]-6-phenyl-2-pyrimidinamine An mPGES-1 inhibitor
- GC43153 CAY10416 Dual cyclooxygenase-2 (COX-2)/5-lipoxygenase (5-LO) inhibitors are potential therapeutic agents for inflammatory diseases and for prostate cancer.
- GC41433 13,14-dihydro Prostaglandin E1 13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound.
- GC40984 ML-148 ML-148 es un inhibidor potente y selectivo de 15-PGDH con una IC50 de 56 nM.
- GC40974 16(S)-Iloprost Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin.
- GC40585 6α-Prostaglandin I1 6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions.
- GC40565 Feprazone Feprazone (DA2370; Prenazone), un anÁlogo de Phenylbutazone, es un agente antiinflamatorio no esteroideo con actividades analgésicas y antipiréticas.
- GC18999 Prostaglandin D1 Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of DGLA, but to date it has not been isolated as a natural product.
- GC18893 CAY10638 Prostaglandins have a short life in vivo because NAD+-dependent 15-hydroxy prostaglandin dehydrogenase (15-PGDH) catalyzes their oxidation to 15-keto metabolites with greatly reduced biological activity.
- GC18882 AF3485 AF3485 is a selective 3-aminocarbazole inhibitor of mPGES-1, blocking the synthesis of PGE2 but not PGF2α in A549 cells stimulated with IL-1β (IC50s = 2.9 and >100 µM, respectively).
- GC18710 CAY10700 Prostaglandin E2 is the major PG synthesized at sites of inflammation and plays an important role in different inflammatory diseases.
- GC18688 CAY10589 Microsomal Prostaglandin E2 Synthase-1 (mPGES-1), with cyclooxygenase-2 (COX-2), synthesizes PGE2, which is directly involved in signaling during inflammation, fever and pain.
- GC18549 CAY10397 Prostaglandins are rapidly inactivated in vivo by the action of 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH).
- GC18271 Polmacoxib El polmacoxib (CG100649) es un fÁrmaco antiinflamatorio no esteroideo (AINE) activo por vÍa oral, el primero de su clase, que es un inhibidor dual de la COX-2 (IC50 de alrededor de 0,1 μg/ml) y la anhidrasa carbÓnica. Polmacoxib inhibe el adenoma colorrectal y el crecimiento tumoral en modelos de ratÓn.