CSP1 |
| Catalog No.GC64061 |
CSP1 es un agonista del receptor ComD1 potente y selectivo, con una IC50 de 10,3 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 172889-49-5
Sample solution is provided at 25 µL, 10mM.
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CSP1 is a potent and selective ComD1 receptor agonist, with an IC50 of 10.3 nM. CSP1 is a major variants of competence-stimulating peptide (CSP), and it can regulate genetic transformation of S. pneumonia by modulating quorum sensing (QS). CSP1 can act as an antibacterial agent[1][2].
[1]. Yang Y, et, al. Structural Characterization of Competence-Stimulating Peptide Analogues Reveals Key Features for ComD1 and ComD2 Receptor Binding in Streptococcus pneumonia. Biochemistry. 2018 Sep 11;57(36):5359-5369.
[2]. Johnsborg O, et, al. A hydrophobic patch in the competence-stimulating Peptide, a pneumococcal competence pheromone, is essential for specificity and biological activity. J Bacteriol. 2006 Mar; 188(5): 1744-9.
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