DSP-1053 |
| Catalog No.GC65014 |
DSP-1053, un derivado de bencilpiperidina, es un potente inhibidor del transportador de serotonina (SERT) con una Ki de 1,02 nM.
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Cas No.: 1176326-76-3
Sample solution is provided at 25 µL, 10mM.
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DSP-1053, a benzylpiperidine derivative, is a potent Serotonin Transporter (SERT) inhibitor with a Ki of 1.02 nM. DSP-1053 shows partial 5-HT1A receptor agonistic activity with a Ki of 5.05 nM. DSP-1053 has antidepressant activity[1].
[1]. Yoshinaga H, et al. Discovery of DSP-1053, a novel benzylpiperidine derivative with potent serotonin transporter inhibitory activity and partial 5-HT1A receptor agonistic activity. Bioorg Med Chem. 2018 May 1;26(8):1614-1627.
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