Epibetulinic acid |
Catalog No.GC60152 |
El Ácido epibetulÍnico exhibe potentes efectos inhibitorios sobre la producciÓn de NO y prostaglandina E2 (PGE2) en macrÓfagos de ratÓn (RAW 264.7) estimulados con endotoxina bacteriana con IC50 de 0,7 y 0,6 μM, respectivamente.
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Cas No.: 38736-77-5
Sample solution is provided at 25 µL, 10mM.
Epibetulinic acid, isolated from the root bark of Maytenus cuzcoina and the leaves of Maytenus chiapensis, exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].
[1]. Reyes CP, et al. Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2. Bioorg Med Chem. 2006 Mar 1;14(5):1573-9.
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